Abstract:
Background: covid-19 severity is disproportionately high in the elderly and people with comorbidities. However, other factors that predispose individuals to increased chances of infection are unclear. Methods: data from 18,600 people screened for covid-19 in mumbai during the outbreak's initial phase, march 7 to june 30, 2020, were used to assess risk factors associated with covid-19 using the odds ratio analysis. Findings: males aged ≥60 years having both diabetes and hypertension were at the highest risk of covid-19 infection (m vs. F or=2.5, 95% ci=1.34–4.67, p = 0.0049). People having both diabetes and hypertension in ≥20 years (or=4.11, 95% ci=3.26–5.20, p <0.0001), diabetes and hypertension independently in 20–39 (or=4.13, 95% ci=2.22–7.70, p <0.0001, or=4.32, 95% ci=2.10–8.88, p = 0.0001) and ≥60 years (or=2.69, 95% ci=1.87–3.87, p <0.0001, or=2.03, 95% ci=1.46–2.82, p <0.0001), chronic renal disease in 20–39 years (or=5.38, 95% ci=1.91–15.09, p = 0.0007) age groups had significantly higher risk of covid-19 infection than those without comorbidity. Quarantined people had significantly lower positive odds (or=0.59, 95% ci=0.53–0.66, p <0.001) than non-quarantined people. Interpretation: our research indicates that the risk of getting covid-19 disease is not equal. When considering sex, age, and comorbidity together, we found that males aged ≥60 years and having both diabetes and hypertension had a significantly high risk of covid-19 infection. Therefore, remedial measures such as vaccination programs should be prioritized for at-risk individuals. Funding: serb, india: sb/s1/covid-2/2020 and seed grant rd/0520-ircchc0–006 from ircc, iit bombay. © 2021 the authors