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Identification of agents targeting FtsZ assembly

PANDA, D; BHATTACHARYA, D; GAO, QH; OZA, PM; LIN, HYJ; HAWKINS, B; HIBBS, DE; GROUNDWATER, PW (FUTURE SCI LTD, 2016)

Filamenting temperature-sensitive mutant Z (FtsZ), an essential cell division protein in bacteria, has recently emerged as an important and exploitable antibacterial target. Cytokinesis in bacteria is regulated by the ...
Immunogenicity of CAR-T Cell Therapeutics: Evidence, Mechanism and Mitigation

KHAN A.N.; CHOWDHURY A.; KARULKAR A.; JAISWAL A.K.; BANIK A.; ASIJA S.; PURWAR R. (Frontiers Media S.A., 2022)

Chimeric antigen receptor t cell (car-t) therapy demonstrated remarkable success in long-term remission of cancers and other autoimmune diseases. Currently, six products (kymriah, yescarta, tecartus, breyanzi, abecma, and ...
Immunomodulatory effects of a concoction of natural bioactive compounds—mechanistic insights

GANGWAR V.; GARG A.; LOMORE K.; KORLA K.; BHAT S.S.; RAO R.P.; RAFIQ M.; KUMAWATH R.; UDDAGIRI B.V.; KAREENHALLI V.V. (MDPI, 2021)

Natural bioactive compounds derived from plant-based products are known for their bio-logical immunomodulatory activities. They possess systemic pleiotropic effects, minimal side effects, and very low toxicities. Plant-based ...
Immunomodulatory nanosystems for treating inflammatory diseases

AHAMAD N.; KAR A.; MEHTA S.; DEWANI M.; RAVICHANDRAN V.; BHARDWAJ P.; SHARMA S.; BANERJEE R. (Elsevier Ltd, 2021)

Inflammatory disease (id) is an umbrella term encompassing all illnesses involving chronic inflammation as the central manifestation of pathogenesis. These include, inflammatory bowel diseases, hepatitis, pulmonary disorders, ...
An immunotherapeutic approach to decipher the role of long non-coding RNAs in cancer progression, resistance and epigenetic regulation of immune cells

VARIER K.M.; DHANDAPANI H.; LIU W.; SONG J.; WANG C.; HU A.; BEN-DAVID Y.; SHEN X.; LI Y.; GAJENDRAN B. (BioMed Central Ltd, 2021)

Immunotherapeutic treatments are gaining attention due to their effective anti-tumor response. Particularly, the revolution of immune checkpoint inhibitors (icis) produces promising outcomes for various cancer types. ...
Impact of Supercritical CO2on Shale Reservoirs and Its Implication for CO2Sequestration

HAZRA B.; VISHAL V.; SETHI C.; CHANDRA D. (American Chemical Society, 2022)

Hydraulic fracturing has transformed the international energy landscape by becoming the go-to method for the exploitation of natural gas from unconventional shale reservoirs. However, in the recent years, the search for ...
In Silico Studies of Active Probe Dynamics in Crowded Media

THEEYANCHERI L.; SAHOO R.; KUMAR P.; CHAKRABARTI R. (American Chemical Society, 2022)

Active systems are made of agents, each of which takes energy from the environment and converts it to directed motion. Therefore, by construction, these systems function out of equilibrium and cannot be described using ...
In-Silico Bioprospecting: Finding Better Enzymes

KAMBLE, A; SRINIVASAN, S; SINGH, H (HUMANA PRESS INC, 2019)

Enzymes are essential biological macromolecules, which catalyse chemical reactions and have impacted the human civilization tremendously. The importance of enzymes as biocatalyst was realized more than a century ago by ...
In-Silico Bioprospecting: Finding Better Enzymes

KAMBLE, A; SRINIVASAN, S; SINGH, H (HUMANA PRESS INC, 2019)

Enzymes are essential biological macromolecules, which catalyse chemical reactions and have impacted the human civilization tremendously. The importance of enzymes as biocatalyst was realized more than a century ago by ...
In-Silico Bioprospecting: Finding Better Enzymes

KAMBLE, A; SRINIVASAN, S; SINGH, H (HUMANA PRESS INC, 2019)

Enzymes are essential biological macromolecules, which catalyse chemical reactions and have impacted the human civilization tremendously. The importance of enzymes as biocatalyst was realized more than a century ago by ...
Inelastic-scattering of x-rays and gamma-rays by inner shell electrons

KANE, PP (ELSEVIER SCIENCE BV, 1992)

A survey is presented of theoretical and experimental studies of inelastic scattering of X-rays and gamma rays by electrons in inner atomic shells. The photon energy range from 2 keV to about 1 MeV is considered. The main ...
Influence of both steric effects and te center dot center dot center dot n intramolecular nonbonded interactions on the stabilization of organotellurium compounds incorporating [2-[1-(3,5-dimethylphenyl)-2-naphthyl]-4,5-dihydro-4,4-dimethyloxazole]

KANDASAMY, K; KUMAR, S; SINGH, HB; WOLMERSHAUSER, G (AMER CHEMICAL SOC, 2003)

A series of novel low-valent organotellurium compounds incorporating [2-[1-(3,5-dimethylphenyl)-2-naphthyl]-4,5-dihydro-4,4-dimethyloxazole] (1) stabilized by (TeN)-N-... nonbonded interactions have been synthesized. The ...
Influence of extrinsic factors on granulation in uasb reactor

TIWARI, MK; GUHA, S; HARENDRANATH, CS; TRIPATHI, S (SPRINGER/PLENUM PUBLISHERS, 2006)

The aim of this mini-review is to synthesize and analyze information on how the process of granulation is affected by environmental and operational conditions in the reactor. The factors reviewed are temperature, pH, ...
Inorganic Nanotubes and Fullerene-like Nanoparticles at the Crossroads between Solid-State Chemistry and Nanotechnology

VISIC, B; PANCHAKARLA, LS; TENNE, R (AMER CHEMICAL SOC, 2017)

Inorganic nanotubes (NTs) and fullerene-like nanoparticles (NPs) of WS2 were discovered some 25 years ago and are produced now on a commercial scale for various applications. This Perspective provides a brief description ...
Input reduction and acceleration techniques in a morphodynamic modeling: A case study of Mumbai harbor

RAMAKRISHNAN, B; SINGH, NP; JEYARAJ, S (ELSEVIER, 2019)

Thane creek, which houses two major commercial ports; Mumbai & Jawaharlal Nehru Ports face periodic siltation problems. The maintenance dredging, carried out to keep navigational channel navigable, incurs a high annual ...
Insights on co-catalyst-promoted enamine formation between dimethylamine and propanal through ab initio and density functional theory study

PATIL, MP; SUNOJ, RB (AMER CHEMICAL SOC, 2007)

The mechanistic details on enamine formation between dimethylamine and propanal are unraveled using the ab initio and density functional theory methods. The addition of secondary amine to the electrophile and simultaneous ...
Insights on Proteomics-Driven Body Fluid-Based Biomarkers of Cervical Cancer

MUKHERJEE A.; PEDNEKAR C.B.; KOLKE S.S.; KATTIMANI M.; DURAISAMY S.; BURLI A.R.; GUPTA S.; SRIVASTAVA S. (MDPI, 2022)

Cervical cancer is one of the top malignancies in women around the globe, which still holds its place despite being preventable at early stages. Gynecological conditions, even maladies like cervical cancer, still experience ...
Instability criteria for hot deformation of materials

MURTY, SVSN; RAO, BN; KASHYAP, BP (ASM INTERNATIONAL, 2000)

Forming and forging processes are among the oldest and most important materials related technologies. New materials technologies centre on the development and widespread use of thermomechanical processing, particularly for ...
Integrated review of stealth technology and its role in airpower

RAO, GA; MAHULIKAR, SP (ROYAL AERONAUTICAL SOC, 2002)

This paper discusses the evolution of airpower and the ever-increasing component of stealth technology in dictating warfare, based on the need felt in the literature to integrate and place them in the right perspective. ...
Intensity-Modulated Photocurrent Spectroscopy and Its Application to Perovskite Solar Cells

RAVISHANKAR, S; RIQUELME, A; SARKAR, SK; GARCIA-BATLLE, M; GARCIA-BELMONTE, G; BISQUERT, J (AMER CHEMICAL SOC, 2019)

Frequency domain techniques are useful tools to characterize processes occurring on different time scales in solar cells and solar fuel devices. Intensity-modulated photocurrent spectroscopy (IMPS) is one such technique ...

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