Please use this identifier to cite or link to this item: https://dspace.library.iitb.ac.in/jspui/handle/100/14003
Title: Comparative Analysis of Routine Laboratory Diagnostic Tests for Rabies
Authors: KADAM, S
SHERIKAR, A
PINGALE, V
Keywords: Mouse Inoculation Test
Modified Counterimmunoelectrophoresis Test
Fluorescent-Antibody Test
Enzyme-Immunoassay
Incubation Period
Virus
Animals
India
Mice
Antigen
Issue Date: 2011
Publisher: INDIAN VIROLOGICAL SOC
Citation: INDIAN JOURNAL OF VIROLOGY,22(2)142-145
Abstract: Present study was undertaken to compare various routine laboratory diagnostic tests for rabies detection. Seller's staining, mouse inoculation test (MIT), Dot-ELISA, Agar gel precipitation test (AGPT) and counter immunoelectrophoresis test (CIET) were the main basic tests performed in the laboratory for the rabies diagnosis. Out of 200 brain specimens, Negri bodies were observed in 52 brain samples by Seller's staining. Rabies virus was isolated in 56 samples by intra-cerebral inoculation in newborn Swiss-albino mice. Dot-ELISA and AGPT could detect rabies antigen in 55 and 57 samples respectively. Comparative analysis revealed that the CIET is the most sensitive and rapid test among performed diagnostic tests.
URI: http://dx.doi.org/10.1007/s13337-011-0052-1
http://dspace.library.iitb.ac.in/jspui/handle/100/14003
ISSN: 0970-2822
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