CONVENIENT SYNTHESIS OF DECALIN SYSTEMS OF BIOACTIVE TERPENOIDS
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New analogues of bioactive terpenoids, forskolin, nimbolide, isozonarol and ambrox have been synthesized using general Diels-Alder reaction of 2-formyl-4,4-dimethyl-cyclohexa-2,5-dienone (7) with 1,2-disubstituted-1,3-dienes (8a-k) which yielded endo- & exo-adducts. The deformylation, epimerisation, angular methylation, reduction and oxidation studies on these adducts have been reported.
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