An efficient and stereoselective synthesis of (2R,2'S)-1-O-(2'-hydroxy-hexadecyl)glycerol and its oxo analogs: Potential antitumour compounds from shark liver oil.

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An efficient and stereoselective synthesis of (2R,2'S)-1-O-(2'-hydroxy-hexadecyl)glycerol and its oxo analogs: Potential antitumour compounds from shark liver oil.

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dc.contributor.author BASKARAN, S en_US
dc.contributor.author BAIG, MHA en_US
dc.contributor.author BANERJEE, S en_US
dc.contributor.author BASKARAN, C en_US
dc.contributor.author BHANU, K en_US
dc.contributor.author DESHPANDE, SP en_US
dc.contributor.author TRIVEDI, GK en_US
dc.date.accessioned 2011-08-23T11:42:50Z en_US
dc.date.accessioned 2011-12-26T12:56:26Z en_US
dc.date.accessioned 2011-12-27T05:45:10Z
dc.date.available 2011-08-23T11:42:50Z en_US
dc.date.available 2011-12-26T12:56:26Z en_US
dc.date.available 2011-12-27T05:45:10Z
dc.date.issued 1996 en_US
dc.identifier.citation TETRAHEDRON, 52(18), 6437-6452 en_US
dc.identifier.issn 0040-4020 en_US
dc.identifier.uri http://dx.doi.org/10.1016/0040-4020(96)00278-5 en_US
dc.identifier.uri http://dspace.library.iitb.ac.in/xmlui/handle/10054/10504 en_US
dc.identifier.uri http://hdl.handle.net/10054/10504
dc.description.abstract Reproducible. high-yielding, cost efficient regio-and stereoselective synthesis of the title compound 3 isolated from Shark Liver Oil has been described. The compound 3 is prepared in an overall yield of 41% from chiral synthon 4 by the sequential reaction of 4 with C-13 Wittig salt: hydrogenation: epoxidation and regioselective opening. The oxo analogs 18 and 19 are prepared from four different achiral synthons by the sequential regioselective opening of the corresponding epoxide with different alcohols. methylation and deprotection strategies. en_US
dc.language.iso en en_US
dc.publisher PERGAMON-ELSEVIER SCIENCE LTD en_US
dc.title An efficient and stereoselective synthesis of (2R,2'S)-1-O-(2'-hydroxy-hexadecyl)glycerol and its oxo analogs: Potential antitumour compounds from shark liver oil. en_US
dc.type Article en_US


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