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dc.contributor.authorKATOCH, Ren_US
dc.contributor.authorTRIVEDI, GKen_US
dc.contributor.authorPHADKE, RSen_US
dc.date.accessioned2011-08-22T08:30:06Zen_US
dc.date.accessioned2011-12-26T12:56:16Zen_US
dc.date.accessioned2011-12-27T05:44:43Z
dc.date.available2011-08-22T08:30:06Zen_US
dc.date.available2011-12-26T12:56:16Zen_US
dc.date.available2011-12-27T05:44:43Z
dc.date.issued1999en_US
dc.identifier.citationBIOORGANIC & MEDICINAL CHEMISTRY, 7(12), 2753-2758en_US
dc.identifier.issn0968-0896en_US
dc.identifier.urihttp://dx.doi.org/10.1016/S0968-0896(99)00216-3en_US
dc.identifier.urihttp://dspace.library.iitb.ac.in/xmlui/handle/10054/10375en_US
dc.identifier.urihttp://hdl.handle.net/10054/10375
dc.description.abstractThe synthesis of a new minimum steric perturbing proxyl nitroxide, which is a derivative of glycerol and contains a stearic acid moiety, has been carried out. Its localization in model membrane L-alpha-dipalmitoyl phosphatidyl choline (DPPC) was ascertained with the help of ESR, DSC, H-1 and P-31 NMR techniques. The nitroxide was used for detecting the changes in the phase transition temperature of the model membranes in the presence and absence of drugs. The permeation of the vasodilating drug epinephrine has also been studied using this spin label. The results prove the potential applicability of the new spin probe in the spin labeling of biomembranes. (C) 1999 . .en_US
dc.language.isoenen_US
dc.publisherPERGAMON-ELSEVIER SCIENCE LTDen_US
dc.subjectModel Membranesen_US
dc.subjectChemistryen_US
dc.subject2'-(3-Alpha-Benzyloxy-24-Norcholan-23-Yl)-2',4',4'-Trimethyl-4',5'-Dihydrooxazo.en_US
dc.subjectNitroxidesen_US
dc.subject.other1-[2-Hydroxy-3-Octadecan-1 '-Oate]Propyl-2 '',2 '',5 '',5 '-Tetramethylen_US
dc.subject.otherPyrolidine-N-Oxyl-3 ''-Carboxylateen_US
dc.subject.otherProxyl Stearateen_US
dc.subject.otherSpin Labelen_US
dc.subject.otherModel Membraneen_US
dc.subject.otherPhase Transitionen_US
dc.title1-[2-Hydroxy-3-octadecan-1'-oate]propyl-2 '',2 '',5 '',5 ''-tetramethyl pyrolidine-N-oxyl-3 ''-carboxylate as a potential spin probe for membrane structure studiesen_US
dc.typeArticleen_US


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