Application of the Suzuki-Miyaura cross-coupling reaction for the modification of phenylalanine peptides

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Title:	Application of the Suzuki-Miyaura cross-coupling reaction for the modification of phenylalanine peptides
Authors:	KOTHA, S LAHIN, K
Keywords:	amino-acid derivatives ring-closing metathesis diels-alder reaction 2+2+2 cycloaddition strategy enyne metathesis tic derivatives solid-phase synthetic approach chemical synthesis drug discovery
Issue Date:	2003
Publisher:	JOHN WILEY & SONS INC
Citation:	BIOPOLYMERS, 69(4), 517-528
Abstract:	We have demonstrated an exceptionally simple and a useful methodology,for modification Of unusual phenylalanine peptides by adapting the building block approach using the Suzuki-Miyaura cross-coupling reaction as a key step. This strategy gave a good overall yield of various modified tri- and pentapeptides that may be useful to prepare various biologically active peptides in a short period of time. (C) 2003 .
URI:	http://dx.doi.org/10.1002/bip.10420 http://dspace.library.iitb.ac.in/xmlui/handle/10054/9333 http://hdl.handle.net/10054/9333
ISSN:	0006-3525
Appears in Collections:	Article

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