Synthesis of novel 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives through the application of rongalite: A synergistic combination of [2+2+2]- and [4+2]-cycloaddition reactions

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Title:	Synthesis of novel 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives through the application of rongalite: A synergistic combination of [2+2+2]- and [4+2]-cycloaddition reactions
Authors:	KOTHA, S BANERJEE, S
Keywords:	phenylethanolamine n-methyltransferase diversity-oriented synthesis natural-product hybrids asymmetric-synthesis amino-acids napieralski reaction constrained analogs peptide antagonists tic derivatives potent
Issue Date:	2007
Publisher:	GEORG THIEME VERLAG KG
Citation:	SYNTHESIS-STUTTGART, (7), 1015-1020
Abstract:	An efficient route for the synthesis of several novel 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) derivatives has been reported. A synergistic combination of [2+2+2]- and [4+2]-cycloaddition reactions has been used for the synthesis of the desired targets.
URI:	http://dx.doi.org/10.1055/s-2007-965946 http://dspace.library.iitb.ac.in/xmlui/handle/10054/7915 http://hdl.handle.net/10054/7915
ISSN:	0039-7881
Appears in Collections:	Article

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