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Please use this identifier to cite or link to this item: http://dspace.library.iitb.ac.in/jspui/handle/10054/774

Title: 2-(2′-Pyridyl)benzimidazole as a fluorescent probe for monitoring protein–surfactant interaction
Authors: MUKHERJEE, TUSHAR KANTI
LAHIRI, PRIYANKA
DATTA, ANINDYA
Keywords: fluorophore
surfactants
monitoring
proteins
Issue Date: 2007
Publisher: Elsevier
Citation: Chemical Physics Letters 438(4-6), 218-223
Abstract: The effectiveness of 2-(2′-pyridyl)benzimidazole (2PBI) as a fluorescent probe of macromolecular interactions is investigated, with the well-known human serum albumin–sodium dodecyl sulfate aggregates as the test system. The second fluorescence band of 2PBI, arising from a proton-transferred state at the surface of negatively charged sodium dodecyl sulfate micelles, is suppressed in the aggregates. The temporal features reflect the change in the relative population of the cationic and normal forms of the fluorophore. Thus, 2PBI is found to be a potentially good fluorophore for the study of complex systems like protein–surfactant aggregates.
URI: http://dx.doi.org/10.1016/j.cplett.2007.03.014
http://hdl.handle.net/10054/774
http://dspace.library.iitb.ac.in/xmlui/handle/10054/774
ISSN: 0009-2614
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