DSpace at IIT Bombay >
IITB Publications >
Please use this identifier to cite or link to this item:
|Title: ||Copper-free and amine-free Sonogashira coupling in air in a mixed aqueous medium by palladium complexes of N/O-functionalized N-heterocyclic carbenes|
|Authors: ||SAMANTARAY, MK|
|Keywords: ||ring-opening polymerization|
|Issue Date: ||2009|
|Publisher: ||ELSEVIER SCIENCE SA|
|Citation: ||JOURNAL OF ORGANOMETALLIC CHEMISTRY, 694(21), 3477-3486|
|Abstract: ||Highly convenient copper-free and amine-free Sonogashira coupling of aryl bromides and iodides with terminal acetylenes under amenable conditions in air and in a mixed aqueous medium are reported using several new, user friendly and robust palladium precatalysts (1-5) of N/O-functionalized N-heterocyclic carbenes (NHCs). In particular, the precatalysts, 1 and 2, were synthesized from the imidazolium chloride salts by the treatment with PdCl(2) in pyridine in presence of K(2)CO(3) as a base while the precatalysts, 3-5, were synthesized from the respective silver complexes by the treatment with (COD) PdCl(2). The DFT studies carried out on the 1-5 complexes suggest the presence of strong NHC-Pd sigma-interactions arising out of deeply buried NHC-Pd sigma-bonding molecular orbitals (MOs) that account for the inert nature of the metal-carbene bonds and also provide insights into the exceptional stability of these precatalysts. (C) 2009|
|Appears in Collections:||Article|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.