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|Title: ||Novel U-bent fiber optic probe for localized surface plasmon resonance based biosensor|
|Authors: ||SAI, VVR|
|Keywords: ||field absorption sensor|
|Issue Date: ||2009|
|Publisher: ||ELSEVIER ADVANCED TECHNOLOGY|
|Citation: ||BIOSENSORS & BIOELECTRONICS, 24(9), 2804-2809|
|Abstract: ||The aim of this study is to develop an optical absorbance based biosensor suitable for wide scale use in resource-poor locales. A sensor for sensitive measurement of refractive index (RI) with the help of optical absorbance properties of gold nanoparticles (GNP) coupled to an efficient optical transducer in the form of a U-bent fiber optic probe is described. A U-bent probe was fabricated by a simple procedure. The absorbance due to the localized surface plasmon resonance (LSPR) of fiber-bound GNP was found to be linear to refractive index changes between 1.33 and 1.35. A U-bent probe of 200 mu m diameter with a bend radius of 0.75 mm gave rise to a sensitivity of 35 Delta A/RIU at 540 nm. The resolution of the sensor probe was 3.8 x 10(-5) RIU. Label-free biosensing was demonstrated using these probes with the help of IgG-anti IgG as bioreceptor-analyte pair. (C) 2009|
|Appears in Collections:||Article|
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