A HIGH YIELDING SYNTHESIS OF (25R)-SPIRO[CYCLOPROPANE-1,2'-(19-NOR-SPIROST-4-EN-22-ALPHA-O)-3-ONE]

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Title:	A HIGH YIELDING SYNTHESIS OF (25R)-SPIRO[CYCLOPROPANE-1,2'-(19-NOR-SPIROST-4-EN-22-ALPHA-O)-3-ONE]
Authors:	DESAI, UR TRIVEDI, GK
Issue Date:	1991
Publisher:	COUNCIL SCIENTIFIC INDUSTRIAL RESEARCH
Citation:	INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 30(7), 635-638
Abstract:	The synthesis of title compound (1) by a series of functional group transformations in a high overall yield from the commercially available diosgenin is described. The synthesis requires 5-alpha, 6-beta-bromohydrin formation, radical-initiated ring formation, regioselective opening of the epoxy ring, and regioselective cyclopropanation as crucial steps.
URI:	http://dspace.library.iitb.ac.in/xmlui/handle/10054/5460 http://hdl.handle.net/10054/5460
ISSN:	0376-4699
Appears in Collections:	Article

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