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Please use this identifier to cite or link to this item: http://dspace.library.iitb.ac.in/jspui/handle/10054/5278

Title: The metabolism of 4-aminobutyrate (GABA) in fungi
Authors: KUMAR, S
PUNEKAR, NS
Keywords: crassa conidial germination
yeast candida-boidinii
amino-acid pools
neurospora-crassa
saccharomyces-cerevisiae
aspergillus-nidulans
gamma-aminobutyrate
coprinus-cinereus
integrator gene
nitrogen-source
Issue Date: 1997
Publisher: CAMBRIDGE UNIV PRESS
Citation: MYCOLOGICAL RESEARCH, 101(), 403-409
Abstract: Information on the genetics and metabolism of 4-aminobutyrate (GABA) in yeasts and fungi is reviewed. In spite of ubiquitous occurrence, there is limited information on its function and biological role. Most fungi utilize GABA both as a carbon and a nitrogen source. Fungal endogenous GABA largely originates from the decarboxylation of L-glutamate and is associated with sporulation/spore metabolism. Whatever its source, GABA is catabolized to succinate via succinicsemialdehyde. Taken together these steps define a potential bypass outside the classical tricarboxylic acid cycle. Evidence for the existence of such a functional bypass in fungi is reviewed. The role of GABA and its metabolism in various facets of fungal biology is gradually emerging.
URI: http://dx.doi.org/10.1017/S0953756296002742
http://dspace.library.iitb.ac.in/xmlui/handle/10054/5278
http://hdl.handle.net/10054/5278
ISSN: 0953-7562
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