DSpace
 

DSpace at IIT Bombay >
IITB Publications >
Article >

Please use this identifier to cite or link to this item: http://dspace.library.iitb.ac.in/jspui/handle/10054/3940

Title: Mica Surface Promotes the Assembly of Cytoskeletal Proteins
Authors: HAMON, L
PANDA, D
SAVARIN, P
JOSHI, V
BERNHARD, J
MUCHER, E
MECHULAM, A
CURMI, PA
PASTRE, D
Keywords: bacterial-cell division
atomic-force microscopy
ftsz
dna
tubulin
polymerization
visualization
degradation
hydrolysis
dynamics
Issue Date: 2009
Publisher: AMER CHEMICAL SOC
Citation: LANGMUIR, 25(6), 3331-3335
Abstract: We report the surface-mediated polymerization of FtsZ protein, the prokaryote homologue of tubulin, by AFM. FtsZ protein can form filaments on mica whereas the bulk FtsZ concentration is orders of magnitude lower than the critical concentration. Surface polymerization is favored by a local increase in protein concentration and requires a high mobility of proteins on the surface. To generalize to other cytoskeleton protein, we also show that mica can initiate the formation of tubulin protofilaments. This study is of particular interest for studying cytoskeletal protein dynamics by AFM but also for the surface autoassembly of nanostructures.
URI: http://dx.doi.org/10.1021/la8035743
http://dspace.library.iitb.ac.in/xmlui/handle/10054/3940
http://hdl.handle.net/10054/3940
ISSN: 0743-7463
Appears in Collections:Article

Files in This Item:

There are no files associated with this item.

View Statistics

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2010  Duraspace - Feedback