DSpace
 

DSpace at IIT Bombay >
IITB Publications >
Article >

Please use this identifier to cite or link to this item: http://dspace.library.iitb.ac.in/jspui/handle/10054/12951

Title: Yagyopathy versus oral and IV drug administration: Evaluation for pulmonary tuberculosis using compartment modeling
Authors: JOSHI, RR
RAGHUVANSHI, M
PANDYA, P
Keywords: inhalation
bioavailability
deposition
absorption
Issue Date: 2006
Publisher: WORLD SCIENTIFIC PUBL CO PTE LTD
Citation: JOURNAL OF BIOLOGICAL SYSTEMS, 14(3), 463-489
Abstract: With pulmonary drug administration gaining more and more importance, there is an obvious need for improvement in the existing methods and search for the newer ones. We have carried out the first ever study on the potentials of yagyopathy in this regard. While introducing this new mode of pulmonary drug administration, we also highlight some preliminary clinical and empirical results on drug inhalation characterization of yagyopathy that indicate its effectiveness in the treatment of pulmonary tuberculosis and thus motivate the present study. We construct mathematical models to evaluate the efficacy of this method of herbal cure vis-a-vis the common modes of oral and intravenous medication. The models are analyzed mathematically for the availability of the drug and other important pharmacokinetic features for the case when the site of infection and hence of desired activation is located in the lungs. Computer simulation experiments and validation are also carried out using available data from relevant empirical studies. The results further support significant potential of yagyopathy especially in terms of higher lung deposits, (bio) availability and residence time. The scope of yagyopathy and related research directions are discussed.
URI: http://dx.doi.org/10.1142/S0218339006001891
http://dspace.library.iitb.ac.in/xmlui/handle/10054/12951
http://hdl.handle.net/10054/12951
ISSN: 0218-3390
Appears in Collections:Article

Files in This Item:

There are no files associated with this item.

View Statistics

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2010  Duraspace - Feedback