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|Title: ||Enantioselective Synthesis of Phenyl-ethanolamines Through Application of Chiral Sulfoxide|
|Authors: ||SIVAKUMAR, AV|
|Keywords: ||asymmetric reduction|
|Issue Date: ||2009|
|Publisher: ||TAYLOR & FRANCIS INC|
|Citation: ||SYNTHETIC COMMUNICATIONS, 39(18), 3338-3347|
|Abstract: ||Efficient enantioselective synthesis of (R)- and (S)-enantiomers of 2-(tert-butylamino)-1-(p-methoxyphenyl)-ethanol has been achieved in high enantiomeric excess by using asymmetric sulfoxide as a chiral auxiliary. The present synthetic approach was further extended to the asymmetric synthesis of (R)-salbutamol.|
|Appears in Collections:||Article|
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