Please use this identifier to cite or link to this item: http://dspace.library.iitb.ac.in/xmlui/handle/10054/11442
Title: Synthesis of highly functionalized phenylalanine derivatives via cross-enyne metathesis reactions
Authors: KOTHA, S
HALDER, S
BRAHMACHARY, E
Keywords: Amino-Acid Derivatives
Olefin Metathesis
Issue Date: 2002
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
Citation: TETRAHEDRON, 58(45), 9203-9208
Abstract: A new method for the synthesis of constrained phenylalanine derivatives is described. In this regard, the simple synthesis of acyclic diene building blocks embodying an alpha-amino acid moiety has been achieved. The diene building blocks have been prepared by cross enyne-metathesis reaction as a key step. The Diels-Alder reaction of the dienes with a dienophile such as dimethyl acetylenedicarboxilate (DMAD) followed by oxidation of the resulting cycloadduct gave highly substituted phenylalanine derivatives. (C) 2002 . .
URI: http://dx.doi.org/10.1016/S0040-4020(02)01178-X
http://dspace.library.iitb.ac.in/xmlui/handle/10054/11442
http://hdl.handle.net/10054/11442
ISSN: 0040-4020
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