One-pot three component alpha-aminoalkylation of conjugated nitroalkenes and nitrodienes

Please use this identifier to cite or link to this item: http://dspace.library.iitb.ac.in/jspui/handle/10054/11129

Title:	One-pot three component alpha-aminoalkylation of conjugated nitroalkenes and nitrodienes
Authors:	RAJESH, K SHANBHAG, P RAGHAVENDRA, M BHARDWAJ, P NAMBOOTHIRI, INN
Keywords:	baylis-hillman reaction methyl vinyl ketone anticancer activity n-sulfinimines cyclic enones lewis base derivatives adducts imidazole aldehydes
Issue Date:	2010
Publisher:	PERGAMON-ELSEVIER SCIENCE LTD
Citation:	TETRAHEDRON LETTERS, 51(5), 846-849
Abstract:	Nitroethylenes possessing aryl, heteroaryl, and alkyl substituents at the beta-position as well as delta-substituted nitrobutadienes undergo facile aminoalkylation at the alpha-position upon treatment with formaldehyde and a secondary amine in the presence of imidazole and trifluoroacetic acid to afford alpha-aminoalkylated nitroalkenes and nitrodienes in good to excellent yield and stereoselectivity. (c) 2009
URI:	http://dx.doi.org/10.1016/j.tetlet.2009.12.015 http://dspace.library.iitb.ac.in/xmlui/handle/10054/11129 http://hdl.handle.net/10054/11129
ISSN:	0040-4039
Appears in Collections:	Article

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