Please use this identifier to cite or link to this item: http://dspace.library.iitb.ac.in/xmlui/handle/10054/11129
Title: One-pot three component alpha-aminoalkylation of conjugated nitroalkenes and nitrodienes
Authors: RAJESH, K
SHANBHAG, P
RAGHAVENDRA, M
BHARDWAJ, P
NAMBOOTHIRI, INN
Keywords: Baylis-Hillman Reaction
Methyl Vinyl Ketone
Anticancer Activity
N-Sulfinimines
Cyclic Enones
Lewis Base
Derivatives
Adducts
Imidazole
Aldehydes
Issue Date: 2010
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
Citation: TETRAHEDRON LETTERS, 51(5), 846-849
Abstract: Nitroethylenes possessing aryl, heteroaryl, and alkyl substituents at the beta-position as well as delta-substituted nitrobutadienes undergo facile aminoalkylation at the alpha-position upon treatment with formaldehyde and a secondary amine in the presence of imidazole and trifluoroacetic acid to afford alpha-aminoalkylated nitroalkenes and nitrodienes in good to excellent yield and stereoselectivity. (c) 2009
URI: http://dx.doi.org/10.1016/j.tetlet.2009.12.015
http://dspace.library.iitb.ac.in/xmlui/handle/10054/11129
http://hdl.handle.net/10054/11129
ISSN: 0040-4039
Appears in Collections:Article

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