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|Title: ||One-pot three component alpha-aminoalkylation of conjugated nitroalkenes and nitrodienes|
|Authors: ||RAJESH, K|
|Keywords: ||baylis-hillman reaction|
methyl vinyl ketone
|Issue Date: ||2010|
|Publisher: ||PERGAMON-ELSEVIER SCIENCE LTD|
|Citation: ||TETRAHEDRON LETTERS, 51(5), 846-849|
|Abstract: ||Nitroethylenes possessing aryl, heteroaryl, and alkyl substituents at the beta-position as well as delta-substituted nitrobutadienes undergo facile aminoalkylation at the alpha-position upon treatment with formaldehyde and a secondary amine in the presence of imidazole and trifluoroacetic acid to afford alpha-aminoalkylated nitroalkenes and nitrodienes in good to excellent yield and stereoselectivity. (c) 2009|
|Appears in Collections:||Article|
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