DSpace at IIT Bombay >
IITB Publications >
Please use this identifier to cite or link to this item:
|Title: ||An efficient and stereoselective synthesis of (2R,2'S)-1-O-(2'-hydroxy-hexadecyl)glycerol and its oxo analogs: Potential antitumour compounds from shark liver oil.|
|Authors: ||BASKARAN, S|
|Issue Date: ||1996|
|Publisher: ||PERGAMON-ELSEVIER SCIENCE LTD|
|Citation: ||TETRAHEDRON, 52(18), 6437-6452|
|Abstract: ||Reproducible. high-yielding, cost efficient regio-and stereoselective synthesis of the title compound 3 isolated from Shark Liver Oil has been described. The compound 3 is prepared in an overall yield of 41% from chiral synthon 4 by the sequential reaction of 4 with C-13 Wittig salt: hydrogenation: epoxidation and regioselective opening. The oxo analogs 18 and 19 are prepared from four different achiral synthons by the sequential regioselective opening of the corresponding epoxide with different alcohols. methylation and deprotection strategies.|
|Appears in Collections:||Article|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.