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Please use this identifier to cite or link to this item: http://dspace.library.iitb.ac.in/jspui/handle/10054/10407

Title: A diethyltartrate-based synthesis of both (-)- and (+)-arundic acid
Authors: FERNANDES, RA
DHALL, A
INGLE, AB
Keywords: claisen rearrangement
therapeutic agent
enantioselective synthesis
(r)-2-propyloctanoic acid
alzheimers-disease
allylic alcohols
(r)-arundic acid
ono-2506
activation
Issue Date: 2009
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
Citation: TETRAHEDRON LETTERS, 50(43), 5903-5905
Abstract: A diethyltartrate-based synthesis of both enantiomers of the acute ischemic stroke therapeutic agent, arundic acid is presented. Separable diastereomers were obtained through the Johnson-Claisen rearrangement of the chiral vicinal diol based on the diethyltartrate skeleton and were converted separately into the two enantiomers of arundic acid. (C) 2009
URI: http://dx.doi.org/10.1016/j.tetlet.2009.08.004
http://dspace.library.iitb.ac.in/xmlui/handle/10054/10407
http://hdl.handle.net/10054/10407
ISSN: 0040-4039
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