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|Title: ||A diethyltartrate-based synthesis of both (-)- and (+)-arundic acid|
|Authors: ||FERNANDES, RA|
|Keywords: ||claisen rearrangement|
|Issue Date: ||2009|
|Publisher: ||PERGAMON-ELSEVIER SCIENCE LTD|
|Citation: ||TETRAHEDRON LETTERS, 50(43), 5903-5905|
|Abstract: ||A diethyltartrate-based synthesis of both enantiomers of the acute ischemic stroke therapeutic agent, arundic acid is presented. Separable diastereomers were obtained through the Johnson-Claisen rearrangement of the chiral vicinal diol based on the diethyltartrate skeleton and were converted separately into the two enantiomers of arundic acid. (C) 2009|
|Appears in Collections:||Article|
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