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| Title: | A diethyltartrate-based synthesis of both (-)- and (+)-arundic acid |
| Authors: | FERNANDES, RA DHALL, A INGLE, AB |
| Keywords: | claisen rearrangement therapeutic agent enantioselective synthesis (r)-2-propyloctanoic acid alzheimers-disease allylic alcohols (r)-arundic acid ono-2506 activation |
| Issue Date: | 2009 |
| Publisher: | PERGAMON-ELSEVIER SCIENCE LTD |
| Citation: | TETRAHEDRON LETTERS, 50(43), 5903-5905 |
| Abstract: | A diethyltartrate-based synthesis of both enantiomers of the acute ischemic stroke therapeutic agent, arundic acid is presented. Separable diastereomers were obtained through the Johnson-Claisen rearrangement of the chiral vicinal diol based on the diethyltartrate skeleton and were converted separately into the two enantiomers of arundic acid. (C) 2009 |
| URI: | http://dx.doi.org/10.1016/j.tetlet.2009.08.004 http://dspace.library.iitb.ac.in/xmlui/handle/10054/10407 http://hdl.handle.net/10054/10407 |
| ISSN: | 0040-4039 |
| Appears in Collections: | Article
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