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Please use this identifier to cite or link to this item: http://dspace.library.iitb.ac.in/jspui/handle/10054/10032

Title: SYNTHESIS, CHEMICAL TRANSFORMATION AND ANTIMICROBIAL ACTIVITY OF A NOVEL CLASS OF NITROOLEFINS - 1,3-DIARYL-2-NITROPROP-1-ENES
Authors: KODUKULLA, RPK
TRIVEDI, GK
VORA, JD
MATHUR, HH
Issue Date: 1994
Publisher: MARCEL DEKKER INC
Citation: SYNTHETIC COMMUNICATIONS, 24(6), 819-832
Abstract: synthesis of novel, biologically active 1,3-diaryl-2-nitroprop-1-enes (4) is reported. The synthesis involves condensation between aromatic aldehydes (1) and beta-aryl nitroethanes (3). The chemical transformation of the nitro group in diaryl nitropropenes to a carbonyl function has resulted in a new route to the synthesis of an alpha-hydroxy analog (7c) of a naturally occurring 3, 3'. 4, 4'-tetramethoxy chalcone. The antimicrobial activity of the 1, 3-diaryl-2-nitroprop-1-enes (4a-j) was tested against three gram positive bacteria, two gram negative bacteria and two fungi. These compounds exhibited broad spectrum and microbial activity.
URI: http://dx.doi.org/10.1080/00397919408011304
http://dspace.library.iitb.ac.in/xmlui/handle/10054/10032
http://hdl.handle.net/10054/10032
ISSN: 0039-7911
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