DSpace at IIT Bombay >
IITB Publications >
Please use this identifier to cite or link to this item:
|Title: ||Synthetic organoselenium compounds as antioxidants: glutathione peroxidase activity|
|Authors: ||MUGESH, G|
|Issue Date: ||2000|
|Publisher: ||ROYAL SOC CHEMISTRY|
|Citation: ||CHEMICAL SOCIETY REVIEWS,29(5)347-357|
|Abstract: ||Organoselenium compounds find applications in organic synthesis, materials synthesis, ligand chemistry and biologically relevant processes. This review deals with the use of various synthetic organoselenium compounds as mimics of glutathione peroxidase (GPx), a selenoenzyme which catalyses the reduction of a variety of hydroperoxides and protects the cell membranes from oxidative damage. The mechanism by which these compounds catalyse the reduction of peroxides is also reviewed. The cyclic selenenamides and diselenides with suitably positioned substituents exert their catalytic activity by a mechanism similar to that of the natural enzyme.|
|Appears in Collections:||Review|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.