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|Title: ||Conducting polymer-based biosensors|
|Authors: ||CONTRACTOR, AQ|
|Issue Date: ||1994|
|Publisher: ||PERGAMON-ELSEVIER SCIENCE LTD|
|Citation: ||ELECTROCHIMICA ACTA,39,1321-1324|
|Abstract: ||The electronic conductivity of polymers such as polyaniline exhibits a strong dependence on the redox and protonation state of the polymer. This property has been utilised to develop a generic biosensor concept. The concept involves immobilization of the appropriate enzyme in the conducting polymer matrix. The enzyme catalyzed reaction of the biomolecule results in a change in redox potential and/or pH of the micro environment in the polymer matrix. This change in the micro environment triggers a change in the electronic conductivity which is monitored. Results shall be presented which provide proof of the above concept. The systems chosen for investigation are glucose/glucose oxidase, urea/urease, neutral lipid/lipase and hemoglobin/pepsin.|
|Appears in Collections:||Proceedings papers|
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