Please use this identifier to cite or link to this item: http://dspace.library.iitb.ac.in/xmlui/handle/100/15744
Title: A Chiron Approach to the Total Synthesis of (-)-Juglomycin A, (+)-Kalafungin, (+)-Frenolicin B, and (+)-Deoxyfrenolicin
Authors: FERNANDES, RA
CHAVAN, VP
MULAY, SV
MANCHOJU, A
Issue Date: 2012
Publisher: AMER CHEMICAL SOC
Citation: JOURNAL OF ORGANIC CHEMISTRY, 77(22)10455-10460
Abstract: A general, efficient, and common strategy for the synthesis of (-)-juglomycin A, (+)-kalafungin, (+)-frenolicin B, and (+)-deoxyfrenolicin is reported here. The strategy involves the synthesis of a key building block alkyne from a cheap chiral pool material, D-glucono-delta-lactone, Dotz benzannulation, oxa-Pictet-Spengler reaction, and H2SO4-mediated epimerization.
URI: http://dx.doi.org/10.1021/jo3019939
http://dspace.library.iitb.ac.in/jspui/handle/100/15744
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