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|Title: ||2-Phenoxyethanol derived diselenide and related compounds; synthesis of a seven-membered seleninate ester|
|Authors: ||TRIPATHI, SK|
|Keywords: ||GLUTATHIONE-PEROXIDASE ACTIVITY|
ACTIVE ORGANOSELENIUM COMPOUND
|Issue Date: ||2011|
|Publisher: ||ROYAL SOC CHEMISTRY|
|Citation: ||ORGANIC & BIOMOLECULAR CHEMISTRY,9(2)581-587|
|Abstract: ||Syntheses of several diorganodiselenides and, in particular, a seven-membered cyclic seleninate ester derived from 2-phenoxyethanol are described. The seleninate ester was obtained from allyl (2-(2-hydroxyethoxy)phenyl) selenide through a series of oxidation and [2,3] sigmatropic rearrangement steps. The ester exhibits good GPx-like activity in the coupled reductase assay.|
|Appears in Collections:||Article|
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