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| Title: | 2-Phenoxyethanol derived diselenide and related compounds; synthesis of a seven-membered seleninate ester |
| Authors: | TRIPATHI, SK SHARMA, S SINGH, HB BUTCHER, RJ |
| Keywords: | GLUTATHIONE-PEROXIDASE ACTIVITY ACTIVE ORGANOSELENIUM COMPOUND ANTIOXIDANT ACTIVITY THIOREDOXIN REDUCTASE REMARKABLE ACTIVITY CATALYTIC-ACTIVITY NMR-SPECTROSCOPY PZ-51 EBSELEN IN-SITU SELENOENZYME |
| Issue Date: | 2011 |
| Publisher: | ROYAL SOC CHEMISTRY |
| Citation: | ORGANIC & BIOMOLECULAR CHEMISTRY,9(2)581-587 |
| Abstract: | Syntheses of several diorganodiselenides and, in particular, a seven-membered cyclic seleninate ester derived from 2-phenoxyethanol are described. The seleninate ester was obtained from allyl (2-(2-hydroxyethoxy)phenyl) selenide through a series of oxidation and [2,3] sigmatropic rearrangement steps. The ester exhibits good GPx-like activity in the coupled reductase assay. |
| URI: | http://dx.doi.org/10.1039/c0ob00038h http://dspace.library.iitb.ac.in/jspui/handle/100/14275 |
| ISSN: | 1477-0520 |
| Appears in Collections: | Article
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