Please use this identifier to cite or link to this item: http://dspace.library.iitb.ac.in/xmlui/handle/100/14203
Title: A concise and improved synthesis of (+)-eleutherin, (+)-allo-eleutherin and a formal synthesis of (+)-nocardione B
Authors: FERNANDES, RA
CHAVAN, VP
MULAY, SV
Keywords: Pyranonaphthoquinone Antibiotics
Eleutherin
Cdc25b
Issue Date: 2011
Publisher: PERGAMON-ELSEVIER SCIENCE LTD
Citation: TETRAHEDRON-ASYMMETRY,22(4)487-492
Abstract: A concise and improved stereoselective synthesis of (+)-eleutherin, (+)-allo-eleutherin and the formal synthesis of (+)-nocardione B is described. The synthesis is based on a Dotz benzannulation and an improved oxa-Pictet-Spengler cyclization as the key steps. The synthesis is achieved in six steps in overall yields of 18% for eleutherin and 20% for allo-eleutherin. (C) 2011 Elsevier Ltd. All rights reserved.
URI: http://dx.doi.org/10.1016/j.tetasy.2011.02.011
http://dspace.library.iitb.ac.in/jspui/handle/100/14203
ISSN: 0957-4166
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