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Please use this identifier to cite or link to this item: http://dspace.library.iitb.ac.in/jspui/handle/100/14082

Title: Cationic lipid enhances assembly of bacterial cell division protein FtsZ: A possible role of bacterial membrane in FtsZ assembly dynamics
Authors: KUCHIBHATLA, A
BELLARE, J
PANDA, D
Keywords: POSITIVELY CHARGED LIPOSOMES
ESCHERICHIA-COLI
SEPTAL RING
GTPASE ACTIVITY
CYTOKINESIS
POLYMERS
TUBULIN
BINDING
ACTIN
PROTOFILAMENTS
Issue Date: 2011
Publisher: ELSEVIER SCIENCE BV
Citation: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,49(4)737-741
Abstract: The assembly of FtsZ plays an important role in bacterial cell division. Lipids in the bacterial cell membrane have been suggested to play a role in directing the site of FtsZ assembly. Using lipid monolayer and bilayer (liposome) systems, we directly examined the effects of cationic lipids on FtsZ assembly. We found that cationic lipids enhanced the assembly of FtsZ in association with an increase in the GTPase activity of FtsZ. The system consisting of lipid monolayer and bilayer (liposome) may mimic the bacterial membrane and therefore, the data might indicate the influence of bacterial membrane on the assembly of FtsZ protofilaments. (C) 2011 Elsevier B.V. All rights reserved.
URI: http://dx.doi.org/10.1016/j.ijbiomac.2011.07.008
http://dspace.library.iitb.ac.in/jspui/handle/100/14082
ISSN: 0141-8130
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