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Please use this identifier to cite or link to this item: http://dspace.library.iitb.ac.in/jspui/handle/100/13871

Title: Synthesis of Maradolipid
Authors: SARPE, VA
KULKARNI, SS
Keywords: ONE-POT PROTECTION
CORD-FACTOR ANALOGS
6,6'-DI-O-ACYLATED ALPHA,ALPHA-TREHALOSES
MYCOBACTERIUM-TUBERCULOSIS
DESICCATION RESISTANCE
TREHALOSE GLYCOLIPIDS
SCALE SYNTHESIS
DERIVATIVES
EFFICIENT
ALBUMIN
Issue Date: 2011
Publisher: AMER CHEMICAL SOC
Citation: JOURNAL OF ORGANIC CHEMISTRY,76(16)6866-6870
Abstract: The first synthesis of maradolipid, a unique dissymmetrically 6,6'-di-O-acylated trehalose glycolipid isolated from C. elegans, is accomplished in five steps starting from trehalose in 45% overall yield. The short synthesis relies on dissymmetrization of trehalose core via regioselective acylation of a 2,3,4,2',3',4'-hexa-O-TMS trehalose 6,6'-diol derivative as a key step.
URI: http://dx.doi.org/10.1021/jo200979n
http://dspace.library.iitb.ac.in/jspui/handle/100/13871
ISSN: 0022-3263
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